Peptide lyophilizates

What are peptides and what do they consist of? 

Peptides are chemical compounds found in the body of living organisms. They are an extremely important building block, performing a number of essential functions. They are essential for the proper functioning of the body in both humans and animals. Peptides are composed of amino acids, forming a shorter or longer peptide bond. There are short peptides, or oligopeptides, and longer polypeptides and longest proteins. Most commonly, peptides consist of between two and ten amino acid residues (peptides), more than ten but less than one hundred amino acid residues (polypeptides) or one hundred or more amino acid residues (proteins). They influence many metabolic processes and fitness, and regulate hormone secretion. A peptide is both insulin and oxytocin.

The action of peptides can be compared to that of hormones. Among other things, their function is to transmit information between different organs and cells. Peptides can also act as certain neurotransmitters. With these chemical compounds, there is no need to worry about serious side effects. They occur very rarely. Taking peptides is associated with numerous benefits for the body. The bioavailability of individual peptides is mainly determined by their specific structure. Most of them have short fragments, so they easily pass through the intestines and reach the target site, the area of influence, in an unchanged form.

What are the different types of peptides and how are they formed?

Peptides can be natural or synthetic. The former as chemical compounds found in the body. Their formation occurs when amino acids join together through a peptide bond. In humans, the formation of peptide chains occurs during protein biosynthesis, which occurs during translation. Synthetic peptides, on the other hand, are produced in the laboratory. They are created to produce a compound that mimics natural peptides. This is possible through the use of bioactive amino acids, which can exhibit a variety of properties. It is very important with peptides that they are administered in the right way. Once they enter the body, they begin to have a relatively rapid effect on the body. When peptides are created synthetically, various synthesis techniques are used in both liquid and solid phases.

Peptides can be ribosomal and non-ribosomal. The former are divided into several forests, depending on how they are formed. Ribosomal peptides primarily function as hormones and signal molecules. A distinction can be made, for example, between gut peptides and pancreatic peptides. It is also worth knowing that some ribosomal peptides exhibit antibiotic activity. Non-ribosomal peptides, on the other hand, are formed by enzymes. They can be found in both plants and fungi and in various unicellular organisms. Non-ribosomal peptides include glutathione, a substance with strong antioxidant activity. Peptides can be released from proteins in various ways - during hydrolysis by digestive enzymes (which takes place in the digestive tract), the fermentation process (microbial activity), enzymatic hydrolysis in vitro.

What functions do peptides have?

Peptides have very different functions, depending on their area of action. They exhibit a protective effect on the body, strengthening its immunity. Susceptibility to infection and disease is reduced. They delay the ageing process. They increase strength and increase endurance, so that higher intensity training becomes possible. Peptides can be combined with each other to achieve the desired effects. In sport, they are primarily taken before training to improve the quality of training. Peptides improve the function of all systems in the body. Peptides affect the nervous system, they can reduce pain, calm you down. They even influence sexual behaviour. They show action against viruses, fungi and bacteria. They can inhibit protein expression. They cause changes in the permeability of cell membranes and affect the release of ATP.

What are the uses of peptides?

Peptides have a wide range of applications and are also used in sports, primarily in bodybuilding. They are a recommended substitute for anabolic hormones - safer and showing very similar efficacy. They have a beneficial effect on the quality of sleep, increasing it. This in turn translates into improved regeneration processes. Accelerated and more effective regeneration is crucial for athletes. It reduces the risk of injury. Peptides regulate metabolism and increase insulin sensitivity. This increases its anabolic effect. By using peptides, one can count on better mineralisation and strengthening of the skeleton. Their beneficial effect on the development of muscle mass is also confirmed. Their intake facilitates and accelerates its building.

There are even peptides that aid weight loss, i.e. accelerate fat burning, weight reduction. A very popular one is peptide in the form of semorelin due to its action similar to growth hormone. It stimulates the pituitary gland to increase its secretion. In the world of bodybuilding, growth hormone is crucial. It enhances the process of building muscle mass and re-educating fat tissue. Peptide supplementation is recommended for people who want to improve the appearance of their physique and accelerate muscle growth. With peptides, bodybuilders can afford greater dietary deviations without suffering negative consequences. With them, it is also not necessary to use a rebound as is the case with steroids.

Taking peptides accelerates the process of lipolysis and simultaneously inhibits lipogenesis. In practice, this translates into more efficient use of fatty acids in the body as an energy source during physical activity. Even in the case of excessive calorie intake, calories are not so easily deposited and converted into fat tissue. Anabolic processes are intensified and energy consumption increases. Peptides facilitate the building of muscle mass, and muscles consume more calories than fat tissue. The most popular peptides for muscle mass are primarily CJC 1295, which is an analogue of GnRH, and CJC 1925 DAC. GRHP 2 and GRHP 6 are very popular in the bodybuilding world.

There are peptides that have a very beneficial effect on joints, improving their regeneration and function. With their help, it becomes possible to increase the mineralisation of bones, to reduce inflammation. This is possible thanks to the improvement of the synthesis process of collagen fibres in the body. The use of peptides reduces pain in the joints. Their structures are strengthened. Their intake shortens the time needed to recover from an injury. Peptides have a strong antioxidant effect. They counteract the destructive effects of oxidative stress on the body. They fight the free radicals that cause it.

Peptides are involved in many skin processes, which is why they are used in cosmetics. They are largely responsible for skin hydration, collagen production, skin renewal and cell regeneration. For the cosmetic and pharmaceutical industry, synthetic peptides are mainly used. These come in the form of cosmetics and have a nurturing effect (this applies to skin, hair and nails). Peptides reduce wrinkles, moisturise the skin, improve firmness, smooth, lighten discolouration and accelerate healing.

How do you store peptides properly?

Peptides must be stored properly in order to retain their original properties for a long time. In this way, their effectiveness will not decrease even after several years. It is very important to protect the peptides from contamination, oxidation. They should be stored in a cool place, protected from sunlight and light. It is recommended to keep them at four degrees Celsius if taken daily for the next few days. Short-term refrigeration at a few degrees Celsius will be sufficient. The easiest way to store peptides is in freeze-dried form due to their lower sensitivity to temperature fluctuations. Their properties remain measureless even when kept at room temperature for at least several weeks to several months.

For long-term storage of peptides, i.e. from several months to several years, it is necessary to reduce the temperature to -80 degrees Celsius. Only in this way will they be able to remain stable. Temperature fluctuations, repeated freezing and thawing, have a very detrimental effect on peptides. This makes it easy for them to degrade. For home use, it will be optimal to keep preparations with peptides, including cosmetics, in the refrigerator. They must be stored at a low temperature, protected from light and shock.

What about the legality of peptides?

The vast majority of available peptides are approved for internal and external use. They are not classified as illegal substances. However, it is important to bear in mind that some peptides are listed as contaminated compounds by the World Anti-Doping Agency, or WADA. If athletes use these types of substances, they have to reckon with the possibility of being detected by anti-doping tests. If someone is not competing, for example in bodybuilding, they do not have to worry about this. On a day-to-day basis, amateurs can use peptides as dietary supplements, i.e. a legal supplement to their menu.