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Powerock Pharma ACTH 1-39 2 mg
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Powerock Pharma ensures reliability and pure ACTH 1-39, which stimulates the adrenal cortex and regulates cortisol levels through HPA axis activation for effective energy mobilization and fat metabolism while supporting research on adaptation to physical stress.
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ACTH 1-39 2 mg
ACTH 1-39 (Adrenocorticotropic Hormone) is an advanced, high-purity peptide representing the full amino acid sequence identical to the natural hormone. This compound was designed for effective research on the hypothalamic-pituitary-adrenal (HPA) axis and stress metabolism. Its action in a laboratory setting is based on the precise stimulation of the adrenal cortex, enabling the analysis of glucocorticoid release. This unique property makes ACTH 1-39 widely applicable in research on energy mobilization, adaptation to exertion, and metabolic homeostasis.
ACTH 1-39 Powerock Pharma - Properties
Discover the potential laboratory properties of ACTH 1-39 that can support research on stress physiology, mobilization of energy reserves, and neuroendocrine system regeneration.
Metabolic Mobilization
Supports research on the release of fatty acids and glucose in response to receptor stimulation.
HPA Axis Activation
Enables precise assessment of adrenal function and functional reserves.
Cortisol Regulation
Stimulates natural steroidogenesis processes, crucial for the model organism's adaptation to stressors.
Regeneration Support
Allows investigation of the impact of stress hormones on repair processes and tissue inflammatory response.
Performance Adaptation
Supports research on endurance and the organism's reaction to extreme physical loads.
Precise Action
High specificity of binding to melanocortin type 2 receptors (MC2R) in the adrenal cortex.
High Purity
≥98% purity confirmed by analytical methods, ideal for stimulation tests.
Research Quality
Manufactured according to GMP and ISO 13485 standards exclusively for laboratory purposes.
How ACTH 1-39 works in laboratory conditions
- MC2R Receptor Agonist: The peptide binds to receptors on the surface of adrenal cortex cells, activating adenylyl cyclase.
- Stimulation of Steroidogenesis: Initiates the process of converting cholesterol into cortisol, which is key for energy metabolism research.
- Substrate Mobilization: In research models, effects on lipolysis and gluconeogenesis are observed, simulating a state of energy readiness.
- Immune Response Modulation: Studies indicate the role of induced glucocorticoids in managing inflammatory states.
- Adaptation Support: Allows analysis of the model organism's mechanisms for coping with stressors (physical and chemical).
Why choose ACTH 1-39 from Powerock Pharma?
At Powerock Pharma, our priority is to provide only the highest quality chemical reagents. Every batch of ACTH 1-39 is manufactured in laboratories compliant with GMP, HACCP, and ISO 13485 standards. Our strict quality control supervision (including HPLC and MS) and use of state-of-the-art testing procedures ensure not only product purity but also its stability and reliability in experiments. Collaboration with leading research units guarantees reproducible results. By choosing Powerock Pharma, you bet on excellence, procedural safety, and unmatched quality of materials for endocrine system research.
Research Protocol
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Method of administration:
ACTH 1-39 as a lyophilizate requires reconstitution. Application in a research environment is most often performed via subcutaneous (s.c.) or intramuscular (i.m.) injection according to the protocol.
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Research timing:
To obtain reliable results (e.g., stimulation tests), the agent is administered at strictly defined time points, often in the morning, to mimic the circadian rhythm.
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Observation duration:
The research cycle is typically short (acute studies) or lasts 2–4 weeks in chronic models, allowing for the assessment of hormonal adaptation.
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Recommended quantity for Model A:
In research on Model A (e.g., female equivalent), the starting dose is often 0.25 mg, with the possibility of calibration depending on the subject's mass.
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Recommended quantity for Model B:
For Model B (e.g., male equivalent), the standard research quantity falls within the range of 0.25 mg to 0.5 mg, adjusted for metabolic goals.
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Monitoring:
Continuous monitoring of cortisol concentration in the serum or saliva of research subjects and recording physiological responses is essential.
Frequently Asked Questions
What is the standard dose in research procedures? ▼
- In stimulation tests, 0.25 mg (250 mcg) is often used. In experimental studies, doses may be increased to 1-2 mg depending on the specifics of Model A or B.
Can the reagent be combined with other substances? ▼
- Yes, ACTH 1-39 is sometimes combined with CRH, BPC-157 (for regeneration research), or GHRP-6 to obtain a broader picture of metabolic and neuroendocrine interactions.
What reactions can be observed in the research model? ▼
- Effects typical of elevated cortisol levels can be observed, such as water retention, changes in glucose levels, or modifications in fat metabolism.
Is the product safe for long-term research? ▼
- Long-term exposure may lead to adrenal cortex hypertrophy in the model organism. It is recommended for use in cycles or for diagnostic (short-term) studies.
How should this product be stored? ▼
- The lyophilizate should be stored at 2–8°C. After reconstitution, the solution should be used immediately or stored under refrigerated conditions for a very short time.
What guarantees the quality of Powerock Pharma reagents? ▼
- Our products are manufactured according to GMP, HACCP, and ISO 13485 standards. Purity ≥98% and substance identity are confirmed by HPLC and MS tests, ensuring no contaminants that could affect the study result.
Calculator for measuring research doses
Tip: 1 MG = 1000 MCG
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